b'V A S H EW O U N D S O L U T I O NVashe Indications and Recommended UseVashe Wound Solution is intended forIt can be applied in the following applications:cleansing, irrigating, moistening, debriding, and removing foreign material, including microorganisms, from:Acute and chronic dermal lesionsStage I-IV pressure ulcersStasis ulcersDiabetic ulcersPost-surgical wounds Packing dressing General woundNegative pressureAdjunctive cleansing wound therapy withdebridement First- and second-degree burns instillation and dwellmodalitiesAbrasions and minor irritations of the skin (NPWT-id)Grafted and donor sitesAppropriate to Treat Pressure Injuries According to Recent NPIAP GuidelinesWith devitalized tissue or suspected biofilm, pressure injuriesLEVEL 1 EVIDENCEusually require debridement or more aggressive use of irrigating solutions. 20 These NPIAP guidelines also cite a peer-reviewed published The recently issued guidelines from the National Pressurepaper in the Evidence Discussion section. 22It compared use Injury Advisory Panel (NPIAP) suggest the use of cleansersof HOCl to normal saline for irrigation of chronic wounds (N=17 with hypochlorous acid antimicrobial preservative. 20Similarindividuals, n=12 had pressure injuries). Irrigation was performed in conjunction with ultrasonic debridement and followed by use of recommendations, for all types of wounds, are supported bysilver dressings in both groups. 22the International Wound Infection Institute (IWII) in its best practices guide. 21 CONCLUSION: Fewer wound complications were observed in the HOCl group (35% vs 80%). The product tested in this Level 1 NPIAP GUIDELINES peer-reviewed study is Vashe Wound Solution.Antiseptic cleansing solutions for use on the wound bedNational Pressure Injury Advisory PanelInternational Wound Infection Instituteinclude super oxidized solutions with hypochlorous acid. 20Cytotoxicity of cleansing solutions may be Safe for use on all 4 stages of pressure injuries concentration-dependent. 20EpidermisDermisNOTE: Cytotoxicity is also an important consideration Fat to the NPIAP, and Vashe as supplied is non-cytotoxic. 12 MuscleBoneStage 1 Stage 2 Stage 3 Stage 4 Use cleansing solutions with antimicrobials to cleanSkin intact Partial loss of dermis Full-thickness skin loss Full-thickness skin losspressure injuries with suspected or confirmed infection. 20 Non-blanchable Shallow open ulcers Fat exposed Exposed bone, muscle, erythema or tendonStage 1 Stage 2 Stage 3 Stage 4Skin intact Partial loss of dermis Full thickness skin loss Full thickness skin lossNon-blanchable Shallow open ulcers Fat exposed Exposed bone, muscle erythema or tendonStage 1 Stage 2 Stage 3 Stage 4Skin intact Partial loss of dermis Full thickness skin loss Full thickness skin lossNon-blanchable Shallow open ulcers Fat exposed Exposed bone, muscle erythema or tendon'